SOFA Score Calculator

The Sequential Organ Failure Assessment model scores six major organ systems on a scale from 0 to 4, where higher points represent greater degrees of dysfunction or failure. The total score is computed by taking the sum of the individual sub-scores across all evaluated systems: SOFA = Respiration (PaO2/FiO2) + Coagulation (Platelets) + Liver (Bilirubin) + Cardiovascular (CVD/Mean Arterial Pressure or vasopressor requirement) + Central Nervous System (Glasgow Coma Scale) + Renal (Creatinine or urine output). The cumulative score ranges from 0 to 24, providing a standardized metric for longitudinal monitoring.

Consider an ICU patient with the following clinical parameter values: Respiration PaO2/FiO2 ratio of 250 yields a sub-score of 2. Platelet count of 80,000/mcL yields a sub-score of 2. Bilirubin level of 2.0 mg/dL yields a sub-score of 1. Cardiovascular assessment showing a mean arterial pressure below 70 mmHg yields a sub-score of 1. Glasgow Coma Scale score of 13 yields a sub-score of 2. Serum creatinine of 2.5 mg/dL yields a sub-score of 2. Summing these individual subsystem values gives a total SOFA score of: 2 (Respiration) + 2 (Coagulation) + 1 (Liver) + 1 (Cardiovascular) + 2 (CNS) + 2 (Renal) = 10. A score of 10 indicates severe multi-organ dysfunction with a significantly elevated risk of adverse clinical outcomes.

Always utilize the most recent laboratory values and physiological measurements to ensure accurate risk stratification. Because a patient's condition can change rapidly in critical care settings, serial daily assessments are far more informative than a single baseline calculation. Trending the score over 48 to 72 hours helps clinicians determine whether organ function is improving or deteriorating under current therapeutic protocols.